Biology:SH3GL2
From HandWiki
Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
Endophilin-A1 is a protein that in humans is encoded by the SH3GL2 gene.[1][2]
Interactions
SH3GL2 has been shown to interact with DNM1,[3][4] Amphiphysin,[3][4] ADAM9,[5] SH3KBP1[6] and ADAM15.[5]
References
- ↑ Giachino C; Lantelme E; Lanzetti L; Saccone S; Bella Valle G; Migone N (Jul 1997). "A novel SH3-containing human gene family preferentially expressed in the central nervous system". Genomics 41 (3): 427–34. doi:10.1006/geno.1997.4645. PMID 9169142.
- ↑ "Entrez Gene: SH3GL2 SH3-domain GRB2-like 2". https://www.ncbi.nlm.nih.gov/gene?Db=gene&Cmd=ShowDetailView&TermToSearch=6456.
- ↑ 3.0 3.1 Micheva, K D; Kay B K; McPherson P S (Oct 1997). "Synaptojanin forms two separate complexes in the nerve terminal. Interactions with endophilin and amphiphysin". J. Biol. Chem. (UNITED STATES) 272 (43): 27239–45. doi:10.1074/jbc.272.43.27239. ISSN 0021-9258. PMID 9341169.
- ↑ 4.0 4.1 Modregger, Jan; Schmidt Anne A; Ritter Brigitte; Huttner Wieland B; Plomann Markus (Feb 2003). "Characterization of Endophilin B1b, a brain-specific membrane-associated lysophosphatidic acid acyl transferase with properties distinct from endophilin A1". J. Biol. Chem. (United States) 278 (6): 4160–7. doi:10.1074/jbc.M208568200. ISSN 0021-9258. PMID 12456676.
- ↑ 5.0 5.1 Howard, L; Nelson K K; Maciewicz R A; Blobel C P (Oct 1999). "Interaction of the metalloprotease disintegrins MDC9 and MDC15 with two SH3 domain-containing proteins, endophilin I and SH3PX1". J. Biol. Chem. (UNITED STATES) 274 (44): 31693–9. doi:10.1074/jbc.274.44.31693. ISSN 0021-9258. PMID 10531379.
- ↑ Soubeyran, Philippe; Kowanetz Katarzyna; Szymkiewicz Iwona; Langdon Wallace Y; Dikic Ivan (Mar 2002). "Cbl-CIN85-endophilin complex mediates ligand-induced downregulation of EGF receptors". Nature (England) 416 (6877): 183–7. doi:10.1038/416183a. ISSN 0028-0836. PMID 11894095. Bibcode: 2002Natur.416..183S.
Further reading
- Ren Y, Fang F, Davey F, Taylor M, Aiton J, Coote P, Yao J, Chen JX, Yan SD & Gunn-Moore FJ. (2008). "Endophilin I expression is increased in the brains of Alzheimer's disease patients.". Journal of Biological Chemistry 283 (9): 5685–91. doi:10.1074/jbc.M707932200. PMID 18167351.
- Reutens AT; Begley CG (2002). "Endophilin-1: a multifunctional protein.". Int. J. Biochem. Cell Biol. 34 (10): 1173–7. doi:10.1016/S1357-2725(02)00063-8. PMID 12127567.
- "EEN encodes for a member of a new family of proteins containing an Src homology 3 domain and is the third gene located on chromosome 19p13 that fuses to MLL in human leukemia.". Proc. Natl. Acad. Sci. U.S.A. 94 (6): 2563–8. 1997. doi:10.1073/pnas.94.6.2563. PMID 9122235. Bibcode: 1997PNAS...94.2563S.
- Ringstad N; Nemoto Y; De Camilli P (1997). "The SH3p4/Sh3p8/SH3p13 protein family: binding partners for synaptojanin and dynamin via a Grb2-like Src homology 3 domain.". Proc. Natl. Acad. Sci. U.S.A. 94 (16): 8569–74. doi:10.1073/pnas.94.16.8569. PMID 9238017. Bibcode: 1997PNAS...94.8569R.
- Micheva KD; Ramjaun AR; Kay BK; McPherson PS (1997). "SH3 domain-dependent interactions of endophilin with amphiphysin.". FEBS Lett. 414 (2): 308–12. doi:10.1016/S0014-5793(97)01016-8. PMID 9315708.
- Micheva KD; Kay BK; McPherson PS (1997). "Synaptojanin forms two separate complexes in the nerve terminal. Interactions with endophilin and amphiphysin.". J. Biol. Chem. 272 (43): 27239–45. doi:10.1074/jbc.272.43.27239. PMID 9341169.
- Howard L; Nelson KK; Maciewicz RA; Blobel CP (1999). "Interaction of the metalloprotease disintegrins MDC9 and MDC15 with two SH3 domain-containing proteins, endophilin I and SH3PX1.". J. Biol. Chem. 274 (44): 31693–9. doi:10.1074/jbc.274.44.31693. PMID 10531379.
- "Identification of the endophilins (SH3p4/p8/p13) as novel binding partners for the beta1-adrenergic receptor.". Proc. Natl. Acad. Sci. U.S.A. 96 (22): 12559–64. 1999. doi:10.1073/pnas.96.22.12559. PMID 10535961. Bibcode: 1999PNAS...9612559T.
- "The SH3 domains of endophilin and amphiphysin bind to the proline-rich region of synaptojanin 1 at distinct sites that display an unconventional binding specificity.". J. Biol. Chem. 274 (45): 32001–7. 1999. doi:10.1074/jbc.274.45.32001. PMID 10542231.
- "The interaction between EEN and Abi-1, two MLL fusion partners, and synaptojanin and dynamin: implications for leukaemogenesis.". Leukemia 14 (4): 594–601. 2000. doi:10.1038/sj.leu.2401692. PMID 10764144.
- "Expression and protein-binding studies of the EEN gene family, new interacting partners for dynamin, synaptojanin and huntingtin proteins.". Biochem. J. 348 (2): 447–58. 2000. doi:10.1042/0264-6021:3480447. PMID 10816441.
- "Selection of ligands by panning of domain libraries displayed on phage lambda reveals new potential partners of synaptojanin 1.". J. Mol. Biol. 307 (5): 1329–39. 2001. doi:10.1006/jmbi.2001.4572. PMID 11292345.
- "Endophilin regulates JNK activation through its interaction with the germinal center kinase-like kinase.". J. Biol. Chem. 276 (31): 28913–9. 2001. doi:10.1074/jbc.M103198200. PMID 11384986.
- Chen-Hwang MC; Chen HR; Elzinga M; Hwang YW (2002). "Dynamin is a minibrain kinase/dual specificity Yak1-related kinase 1A substrate.". J. Biol. Chem. 277 (20): 17597–604. doi:10.1074/jbc.M111101200. PMID 11877424.
- "Cbl-CIN85-endophilin complex mediates ligand-induced downregulation of EGF receptors.". Nature 416 (6877): 183–7. 2002. doi:10.1038/416183a. PMID 11894095. Bibcode: 2002Natur.416..183S.
- "The endophilin-CIN85-Cbl complex mediates ligand-dependent downregulation of c-Met.". Nature 416 (6877): 187–90. 2002. doi:10.1038/416187a. PMID 11894096. Bibcode: 2002Natur.416..187P.
- "Alix (ALG-2-interacting protein X), a protein involved in apoptosis, binds to endophilins and induces cytoplasmic vacuolization.". J. Biol. Chem. 277 (32): 29108–15. 2002. doi:10.1074/jbc.M204019200. PMID 12034747.
- "CIN85 participates in Cbl-b-mediated down-regulation of receptor tyrosine kinases.". J. Biol. Chem. 277 (42): 39666–72. 2002. doi:10.1074/jbc.M205535200. PMID 12177062.
- Haglund K; Shimokawa N; Szymkiewicz I; Dikic I (2002). "Cbl-directed monoubiquitination of CIN85 is involved in regulation of ligand-induced degradation of EGF receptors.". Proc. Natl. Acad. Sci. U.S.A. 99 (19): 12191–6. doi:10.1073/pnas.192462299. PMID 12218189. Bibcode: 2002PNAS...9912191H.
- "Endophilin mutations block clathrin-mediated endocytosis but not neurotransmitter release.". Cell 109 (1): 101–12. 2002. doi:10.1016/S0092-8674(02)00688-8. PMID 11955450.
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