Biology:SLC5A8
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Sodium-coupled monocarboxylate transporter 1 is a protein that in humans is encoded by the SLC5A8 gene.[1][2][3]
See also
References
- ↑ "Identification and characterization of a putative human iodide transporter located at the apical membrane of thyrocytes". J Clin Endocrinol Metab 87 (7): 3500–3. Jul 2002. doi:10.1210/jc.87.7.3500. PMID 12107270.
- ↑ "SLC5A8, a sodium transporter, is a tumor suppressor gene silenced by methylation in human colon aberrant crypt foci and cancers". Proc Natl Acad Sci U S A 100 (14): 8412–7. Jul 2003. doi:10.1073/pnas.1430846100. PMID 12829793.
- ↑ "Entrez Gene: SLC5A8 solute carrier family 5 (iodide transporter), member 8". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=160728.
Further reading
- "SLC5A8 (SMCT1)-mediated transport of butyrate forms the basis for the tumor suppressive function of the transporter". Life Sci. 78 (21): 2419–25. 2006. doi:10.1016/j.lfs.2005.10.028. PMID 16375929.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932.
- "Functional identification of SLC5A8, a tumor suppressor down-regulated in colon cancer, as a Na(+)-coupled transporter for short-chain fatty acids". J. Biol. Chem. 279 (14): 13293–6. 2004. doi:10.1074/jbc.C400059200. PMID 14966140.
- "Expression of the apical iodide transporter in human thyroid tissues: a comparison study with other iodide transporters". J. Clin. Endocrinol. Metab. 89 (3): 1423–8. 2004. doi:10.1210/jc.2003-030542. PMID 15001644.
- "Shared epigenetic mechanisms in human and mouse gliomas inactivate expression of the growth suppressor SLC5A8". Cancer Res. 65 (9): 3617–23. 2005. doi:10.1158/0008-5472.CAN-05-0048. PMID 15867356.
- "Na+/monocarboxylate transport (SMCT) protein expression correlates with survival in colon cancer: Molecular characterization of SMCT". Proc. Natl. Acad. Sci. U.S.A. 103 (19): 7270–5. 2006. doi:10.1073/pnas.0602365103. PMID 16670197.
- "Association of aberrant methylation of tumor suppressor genes with tumor aggressiveness and BRAF mutation in papillary thyroid cancer". Int. J. Cancer 119 (10): 2322–9. 2006. doi:10.1002/ijc.22110. PMID 16858683.
- "Transport of nicotinate and structurally related compounds by human SMCT1 (SLC5A8) and its relevance to drug transport in the mammalian intestinal tract". Pharm. Res. 24 (3): 575–84. 2007. doi:10.1007/s11095-006-9176-1. PMID 17245649.
- "Establishing a Definitive Stoichiometry for the Na+/Monocarboxylate Cotransporter SMCT1". Biophys. J. 93 (7): 2325–31. 2007. doi:10.1529/biophysj.107.108555. PMID 17526579.
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