Biology:SMARCA1
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Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
Probable global transcription activator SNF2L1 is a protein that in humans is encoded by the SMARCA1 gene.[1][2][3]
The protein encoded by this gene is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. Two transcript variants encoding different isoforms have been found for this gene.[3]
References
- ↑ "Cloning of human and bovine homologs of SNF2/SWI2: a global activator of transcription in yeast S. cerevisiae". Nucleic Acids Res 20 (17): 4649–55. Oct 1992. doi:10.1093/nar/20.17.4649. PMID 1408766.
- ↑ "Isolation of human NURF: a regulator of Engrailed gene expression". EMBO J 22 (22): 6089–100. Nov 2003. doi:10.1093/emboj/cdg582. PMID 14609955.
- ↑ 3.0 3.1 "Entrez Gene: SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6594.
Further reading
- "WSTF-ISWI chromatin remodeling complex targets heterochromatic replication foci.". EMBO J. 21 (9): 2231–41. 2002. doi:10.1093/emboj/21.9.2231. PMID 11980720.
- "Identification of the phosphotyrosine proteome from thrombin activated platelets.". Proteomics 2 (6): 642–8. 2003. doi:10.1002/1615-9861(200206)2:6<642::AID-PROT642>3.0.CO;2-I. PMID 12112843.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. 2004. doi:10.1038/ng1285. PMID 14702039.
- "A tissue-specific, naturally occurring human SNF2L variant inactivates chromatin remodeling.". J. Biol. Chem. 279 (43): 45130–8. 2004. doi:10.1074/jbc.M406212200. PMID 15310751.
- "Roles of Brahma and Brahma/SWI2-related gene 1 in hypoxic induction of the erythropoietin gene.". J. Biol. Chem. 279 (45): 46733–41. 2004. doi:10.1074/jbc.M409002200. PMID 15347669.
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. 2004. doi:10.1101/gr.2596504. PMID 15489334.
- "CECR2, a protein involved in neurulation, forms a novel chromatin remodeling complex with SNF2L.". Hum. Mol. Genet. 14 (4): 513–24. 2005. doi:10.1093/hmg/ddi048. PMID 15640247.
- "The DNA sequence of the human X chromosome.". Nature 434 (7031): 325–37. 2005. doi:10.1038/nature03440. PMID 15772651. Bibcode: 2005Natur.434..325R.
- "The imitation switch protein SNF2L regulates steroidogenic acute regulatory protein expression during terminal differentiation of ovarian granulosa cells.". Mol. Endocrinol. 20 (10): 2406–17. 2006. doi:10.1210/me.2005-0213. PMID 16740656.
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