Biology:SPNS2
From HandWiki
Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
Spinster homolog 2 (Drosophila) is a protein that in humans is encoded by the SPNS2 gene.[1]
Model organisms
The orthologous protein in zebrafish has been shown to transport sphingosine-1-phosphate (S1P) out of cells during vascular development, and human SPNS2 can transport S1P analogues, including the immunomodulating drug FTY720-P.[2][3]
References
- ↑ "Spinster homolog 2 (Drosophila)". https://www.ncbi.nlm.nih.gov/gene/124976.
- ↑ "The sphingolipid transporter spns2 functions in migration of zebrafish myocardial precursors". Science 323 (5913): 524–7. January 2009. doi:10.1126/science.1167449. PMID 19074308. Bibcode: 2009Sci...323..524K.
- ↑ "The sphingosine 1-phosphate transporter, SPNS2, functions as a transporter of the phosphorylated form of the immunomodulating agent FTY720". The Journal of Biological Chemistry 286 (3): 1758–66. January 2011. doi:10.1074/jbc.M110.171116. PMID 21084291.
 |  |
