Biology:SPRY3
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Short description: Protein-coding gene in the species Homo sapiens
Generic protein structure example |
Protein sprouty homolog 3 is a protein that in humans is encoded by the SPRY3 gene.[1][2]
The SPRY3 gene is one of the genes found in the pseudoautosomal regions of the human sex chromosomes (i.e. those 19 genes that are found on both the X and Y chromosome). It is located in the PAR2 region.
References
- ↑ "sprouty encodes a novel antagonist of FGF signaling that patterns apical branching of the Drosophila airways". Cell 92 (2): 253–63. Feb 1998. doi:10.1016/S0092-8674(00)80919-8. PMID 9458049.
- ↑ "Entrez Gene: SPRY3 sprouty homolog 3 (Drosophila)". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10251.
Further reading
- "Differentially regulated and evolved genes in the fully sequenced Xq/Yq pseudoautosomal region.". Hum. Mol. Genet. 9 (3): 395–401. 2000. doi:10.1093/hmg/9.3.395. PMID 10655549.
- "Sprouty proteins are targeted to membrane ruffles upon growth factor receptor tyrosine kinase activation. Identification of a novel translocation domain.". J. Biol. Chem. 275 (42): 32837–45. 2000. doi:10.1074/jbc.M002156200. PMID 10887178.
- "The cysteine-rich sprouty translocation domain targets mitogen-activated protein kinase inhibitory proteins to phosphatidylinositol 4,5-bisphosphate in plasma membranes.". Mol. Cell. Biol. 22 (22): 7953–66. 2002. doi:10.1128/MCB.22.22.7953-7966.2002. PMID 12391162.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. 2004. doi:10.1038/ng1285. PMID 14702039.
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. 2004. doi:10.1101/gr.2596504. PMID 15489334.
- "Human placental Hofbauer cells express sprouty proteins: a possible modulating mechanism of villous branching.". Placenta 26 (6): 476–83. 2005. doi:10.1016/j.placenta.2004.08.008. PMID 15950061.
- "Maintenance of X- and Y-inactivation of the pseudoautosomal (PAR2) gene SPRY3 is independent from DNA methylation and associated to multiple layers of epigenetic modifications.". Hum. Mol. Genet. 15 (7): 1123–32. 2006. doi:10.1093/hmg/ddl027. PMID 16500999.
- "A functional interaction between sprouty proteins and caveolin-1.". J. Biol. Chem. 281 (39): 29201–2912. 2006. doi:10.1074/jbc.M603921200. PMID 16877379.
External links
- SPRY3 human gene location in the UCSC Genome Browser.
- SPRY3 human gene details in the UCSC Genome Browser.
Original source: https://en.wikipedia.org/wiki/SPRY3.
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