Biology:SQ1002
From HandWiki
SQ1002_RNA | |
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Consensus secondary structure and sequence conservation of Clostridioides difficile sRNA SQ1002 | |
Identifiers | |
Symbol | SQ1002_RNA |
Rfam | RF03533 |
Other data | |
RNA type | Gene; sRNA |
GO | 0070928 |
SO | 0000370 |
PDB structures | PDBe |
SQ1002 is a 191nt small RNA identified in Clostridioides difficile 630 by RNA deep sequencing and confirmed by Northern blot and RT-PCR.[1] Extremities were confirmed by 5’ and 3’-RACE.
This RNA is found in several C. difficile strains at syntenic positions between a putative acyltransferase gene and a ferrous iron transport gene. No homologs were found outside C. difficile, although a putative paralog was found in C. difficile 630, located between a tryptophanyl-tRNA synthetase gene and a pseudogene.
Due to lack of sequence variation, the proposed secondary structure is not supported by any covariation and should be considered speculative.
References
- ↑ Soutourina OA, Monot M, Boudry P, Saujet L, Pichon C, Sismeiro O (2013). "Genome-wide identification of regulatory RNAs in the human pathogen Clostridium difficile.". PLOS Genet 9 (5): e1003493. doi:10.1371/journal.pgen.1003493. PMID 23675309.
External links
Original source: https://en.wikipedia.org/wiki/SQ1002.
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