Biology:Scytalidopepsin A
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Scytalidopepsin A | |||||||||
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Identifiers | |||||||||
EC number | 3.4.23.31 | ||||||||
CAS number | 42613-34-3 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Scytalidopepsin A (EC 3.4.23.31, Scytalidium aspartic proteinase A, Scytalidium lignicolum aspartic proteinase, Scytalidium lignicolum aspartic proteinase A-2, Scytalidium lignicolum aspartic proteinase A-I, Scytalidium lignicolum aspartic proteinase C, Scytalidium lignicolum carboxyl proteinase, Scytalidium lignicolum acid proteinase) is an enzyme.[1][2][3] This enzyme catalyses the following chemical reaction
- Hydrolysis of proteins with specificity similar to that of pepsin A, but also cleaves Cys(SO3H)7-Gly and Leu17-Val in the B chain of insulin
This enzyme is isolated from the fungus Scytalidium lignicolum.
References
- ↑ "Purification and some enzymatic properties of acid protease A and B of Scytalidium lignicolum ATCC 24568". Agric. Biol. Chem. 38: 2435–2444. 1974. doi:10.1271/bbb1961.38.2435.
- ↑ "Action of Scytalidium lignicolum acid proteases on insulin B-chain". Agric. Biol. Chem. 40: 1221–1225. 1976. doi:10.1271/bbb1961.40.1221.
- ↑ "Purification and characterization of acid proteinase C of Scytalidium lignicolum ATCC 24568". Agric. Biol. Chem. 50: 651–658. 1986. doi:10.1271/bbb1961.50.651.
External links
- Scytalidopepsin+A at the US National Library of Medicine Medical Subject Headings (MeSH)
Original source: https://en.wikipedia.org/wiki/Scytalidopepsin A.
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