Biology:Serostatus
Serostatus refers to the presence or absence of a serological marker in the blood. The presence of detectable levels of a specific marker within the serum is considered seropositivity, while the absence of such levels is considered seronegativity.
HIV/AIDS
The term serostatus is commonly used in HIV/AIDS prevention efforts. In the late 20th and early 21st centuries, social advocacy has emphasized the importance of learning one's HIV/AIDS serostatus in an effort to curtail the spread of the disease.[1]
Autoimmune disease
Researchers have investigated the effects of autoantibody serostatus on autoimmune disease presentation.[2][3][4] Study of seronegative patient populations has led to the identification of additional autoantibodies that could potentially help with diagnosis.[5][6]
See also
References
- ↑ Janssen, Robert S.; Holtgrave, David R.; Valdiserri, Ronald O. et al. (July 2001). "The Serostatus Approach to Fighting the HIV Epidemic: prevention strategies for infected individuals". American Journal of Public Health (American Public Health Association) 91 (7): 1019–1024. doi:10.2105/AJPH.91.7.1019. ISSN 1541-0048. PMID 11441723.
- ↑ Jarius, Sven; Ruprecht, Klemens; Wildemann, Brigitte et al. (January 2012). "Contrasting disease patterns in seropositive and seronegative neuromyelitis optica: A multicentre study of 175 patients". Journal of Neuroinflammation (BioMed Central) 9 (1): 14. doi:10.1186/1742-2094-9-14. PMID 22260418.
- ↑ Ajeganova, Sofia; Huizinga, Tom W J (November 2014). "Rheumatoid arthritis: Seronegative and seropositive RA: alike but different?". Nature Reviews Rheumatology (Nature Publishing Group) 11 (1): 8–9. doi:10.1038/nrrheum.2014.194. ISSN 1759-4804. PMID 25403158.
- ↑ Balasubramanian, Gokulakrishnan; Sugumar, Aravind; Smyrk, Thomas C et al. (2012). "Demystifying seronegative autoimmune pancreatitis". Pancreatology (Elsevier) 12 (4): 289–294. doi:10.1016/j.pan.2012.05.003. PMID 22898628. http://www.pancreatology.net/article/S1424-3903%2812%2900129-9/abstract.
- ↑ Somers, Klaartje; Geusens, Piet; Elewaut, Dirk et al. (February 2011). "Novel autoantibody markers for early and seronegative rheumatoid arthritis". Journal of Autoimmunity (Elsevier) 36 (1): 33–46. doi:10.1016/j.jaut.2010.10.003. ISSN 0896-8411. PMID 21071175.
- ↑ Pevzner, Alexandra; Schoser, Benedikt; Peters, Katja et al. (August 2011). "Anti-LRP4 autoantibodies in AChR- and MuSK-antibody-negative myasthenia gravis" (PDF). Journal of Neurology (Springer-Verlag) 259 (3): 427–435. doi:10.1007/s00415-011-6194-7. ISSN 1432-1459. PMID 21814823. https://www.researchgate.net/publication/51545644.
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