Biology:Specific ventilation
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Short description: Measure of gas entering a region of the lung
In respiratory physiology, specific ventilation is defined as the ratio of the volume of gas entering a region of the lung (ΔV) following an inspiration, divided by the end-expiratory volume (V0) of that same lung region:
SV = ΔV⁄V0
It is a dimensionless quantity. For the whole human lung, given an indicative tidal volume of 0.6 L and a functional residual capacity of 2.5 L, average SV is of the order of 0.24.
The distribution of specific ventilation within the lung can be inferred using Multiple Breath Washout (MBW) experiments [1] or imaging techniques such as Positron Emission Tomography (PET) using 13N, Magnetic Resonance Imaging (MRI) using either hyperpolarized gas (3He, 129Xe) or proton MRI (oxygen enhanced imaging).
References
- ↑ Lewis et al, S. M. Lewis, J. W. Evans, and A. A. Jalowayski. Continuous distributions of specific ventilation recovered from inert gas washout, Journal of Applied Physiology, 1978 vol. 44 no. 3 416-423
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