Biology:TCEAL4
From HandWiki
Short description: Protein-coding gene in the species Homo sapiens
Generic protein structure example |
Transcription elongation factor A protein-like 4 is a protein that in humans is encoded by the TCEAL4 gene.[1][2]
This gene encodes a member of the transcription elongation factor A (SII)-like (TCEAL] gene family. Members of this family contain TFA domains and may function as nuclear phosphoproteins that modulate transcription in a promoter context-dependent manner. Multiple family members are located on the X chromosome. Alternative splicing occurs for this gene; however, the full-length nature of all transcript variants has not yet been described.[2]
References
- ↑ "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat Genet 36 (1): 40–5. Dec 2003. doi:10.1038/ng1285. PMID 14702039.
- ↑ 2.0 2.1 "Entrez Gene: TCEAL4 transcription elongation factor A (SII)-like 4". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=79921.
Further reading
- "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene 138 (1–2): 171–4. 1994. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
- "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene 200 (1–2): 149–56. 1997. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
- "Genomic structure and chromosomal localization of TCEAL1, a human gene encoding the nuclear phosphoprotein p21/SIIR". Genomics 56 (2): 217–20. 1999. doi:10.1006/geno.1998.5705. PMID 10051408.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "[Cloning of human B lymphocyte activation-related novel gene]". Zhongguo Yi Xue Ke Xue Yuan Xue Bao 23 (1): 27–31. 2004. PMID 12905813.
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. 2004. doi:10.1101/gr.2596504. PMID 15489334.
- "The DNA sequence of the human X chromosome". Nature 434 (7031): 325–37. 2005. doi:10.1038/nature03440. PMID 15772651. Bibcode: 2005Natur.434..325R.
- "Down-regulation of transcription elongation factor A (SII) like 4 (TCEAL4) in anaplastic thyroid cancer". BMC Cancer 6: 260. 2006. doi:10.1186/1471-2407-6-260. PMID 17076909.
- "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell 127 (3): 635–48. 2006. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
