Biology:TNPO2

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Short description: Protein-coding gene in the species Homo sapiens


A representation of the 3D structure of the protein myoglobin showing turquoise α-helices.
Generic protein structure example

Transportin-2 is a protein that in humans is encoded by the TNPO2 gene.[1][2][3]

Interactions

TNPO2 has been shown to interact with NXF1,[2] NUP98[4] and Ran.[2]

References

  1. ↑ "Transportin-mediated nuclear import of heterogeneous nuclear RNP proteins". The Journal of Cell Biology 138 (6): 1181–92. September 1997. doi:10.1083/jcb.138.6.1181. PMID 9298975. 
  2. ↑ 2.0 2.1 2.2 "Karyopherin beta 2B participates in mRNA export from the nucleus". Proceedings of the National Academy of Sciences of the United States of America 99 (22): 14195–9. October 2002. doi:10.1073/pnas.212518199. PMID 12384575. Bibcode: 2002PNAS...9914195S. 
  3. ↑ "Entrez Gene: TNPO2 transportin 2 (importin 3, karyopherin beta 2b)". https://www.ncbi.nlm.nih.gov/gene?Db=gene&Cmd=ShowDetailView&TermToSearch=30000. 
  4. ↑ "The nucleoporin Nup98 is a site for GDP/GTP exchange on ran and termination of karyopherin beta 2-mediated nuclear import". The Journal of Biological Chemistry 275 (40): 31289–96. October 2000. doi:10.1074/jbc.M004651200. PMID 10875935. 

Further reading