Biology:Translational efficiency
From HandWiki
In cell biology, translational efficiency or translation efficiency is the rate of mRNA translation into proteins within cells. It has been measured in protein per mRNA per hour.[1] Several RNA elements within mRNAs have been shown to affect the rate. These include miRNA and protein binding sites. RNA structure may also affect translational efficiency through the altered protein or microRNA binding.[2]
See also
References
- ↑ Schwanhäusser, Björn; Busse, Dorothea; Li, Na; Dittmar, Gunnar; Schuchhardt, Johannes; Wolf, Jana; Chen, Wei; Selbach, Matthias (May 2011). "Global quantification of mammalian gene expression control". Nature 473 (7347): 337–342. doi:10.1038/nature10098. PMID 21593866. Bibcode: 2011Natur.473..337S. http://edoc.mdc-berlin.de/11664/1/11664oa.pdf.
- ↑ Lu, YF; Mauger, DM; Goldstein, DB; Urban, TJ; Weeks, KM; Bradrick, SS (4 November 2015). "IFNL3 mRNA structure is remodeled by a functional non-coding polymorphism associated with hepatitis C virus clearance.". Scientific Reports 5: 16037. doi:10.1038/srep16037. PMID 26531896. Bibcode: 2015NatSR...516037L.
External links
- [1] Transterm database online
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