Biology:Type IV filament

From HandWiki

The type IV filament superfamily (TFF) is a group of fibrous protein structures that includes a set of cell projections with evolutionarily related membrane proteins.[1] The TFF family seems to have originated in the last universal common ancestor, from where it diversified into archaella, type IV pili, type II secretion systems, and the Tad pili.[2] Complexes in the TFF superfamily are unified by the presence of the eponymous type IV pilin, an AAA+ ATPase, an integral (cytoplasmic) membrane (IM) platform, and (with the exception of MSH) a prepilin peptidase.[2]

References

  1. ↑ "Exceptionally widespread nanomachines composed of type IV pilins: the prokaryotic Swiss Army knives". FEMS Microbiology Reviews 39 (1): 134–54. January 2015. doi:10.1093/femsre/fuu001. PMID 25793961. 
  2. ↑ 2.0 2.1 "Diversification of the type IV filament superfamily into machines for adhesion, protein secretion, DNA uptake, and motility". PLOS Biology 17 (7): e3000390. July 2019. doi:10.1371/journal.pbio.3000390. PMID 31323028. 




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