Biology:U6atac minor spliceosomal RNA
From HandWiki
| U6atac minor spliceosomal RNA | |
|---|---|
 Predicted secondary structure and sequence conservation of U6atac | |
| Identifiers | |
| Symbol | U6atac |
| Rfam | RF00619 |
| Other data | |
| RNA type | Gene; snRNA; splicing |
| Domain(s) | Eukaryota |
| GO | 0000355 0000369 0030622 0030627 0005691 |
| SO | 0000274 |
| PDB structures | PDBe |
U6atac minor spliceosomal RNA is a non-coding RNA which is an essential component of the minor U12-type spliceosome complex. The U12-type spliceosome is required for removal of the rarer class of eukaryotic introns (AT-AC, U12-type).[1]
U6atac snRNA is proposed to form a base-paired complex with another spliceosomal RNA U4atac via two stem loop regions. These interacting stem loops have been shown to be required for in vivo splicing.[2] U6atac is the functional analog of U6 spliceosomal RNA in the major U2-type spliceosomal complex.[2]
References
- ↑ "Evolutionary conservation of minor U12-type spliceosome between plants and humans". RNA 11 (7): 1095–1107. 2005. doi:10.1261/rna.2440305. PMID 15987817.
- ↑ 2.0 2.1 "A revised model for U4atac/U6atac snRNA base pairing". RNA 8 (2): 125–128. 2002. doi:10.1017/S1355838202017156. PMID 11911359.
- "Conservation of functional features of U6atac and U12 snRNAs between vertebrates and higher plants". RNA 5 (4): 525–538. 1999. doi:10.1017/S1355838299982213. PMID 10199569.
External links
fr:ARN splicéosomal U4atac
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