Biology:UNC5A

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A representation of the 3D structure of the protein myoglobin showing turquoise α-helices.
Generic protein structure example

Netrin receptor UNC5A is a protein that in humans is encoded by the UNC5A gene.[1]

UNC5A belongs to a family of netrin-1 (MIM 601614) receptors thought to mediate the chemorepulsive effect of netrin-1 on specific axons. For more information on UNC5 proteins, see UNC5C (MIM 603610).[supplied by OMIM][1]

Interactions

UNC5A has been shown to interact with MAGED1.[2]

References

  1. 1.0 1.1 "Entrez Gene: UNC5A unc-5 homolog A (C. elegans)". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=90249. 
  2. "UNC5H1 induces apoptosis via its juxtamembrane region through an interaction with NRAGE". The Journal of Biological Chemistry 278 (19): 17483–90. May 2003. doi:10.1074/jbc.M300415200. PMID 12598531. 

Further reading