Biology:VPS52

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A representation of the 3D structure of the protein myoglobin showing turquoise α-helices.
Generic protein structure example

Vacuolar protein sorting-associated protein 52 homolog is a protein that in humans is encoded by the VPS52 gene.[1][2]

This gene encodes a protein that is similar to the yeast suppressor of actin mutations 2 gene. The yeast protein forms a subunit of the tetrameric Golgi-associated retrograde protein complex that is involved in vesicle trafficking from both early and late endosomes, back to the trans-Golgi network. This gene is located on chromosome 6 in a head-to-head orientation with the gene encoding ribosomal protein S18.[2]

References

  1. "Identification of a novel highly conserved gene in the centromeric part of the major histocompatibility complex". Genomics 52 (3): 298–304. Dec 1998. doi:10.1006/geno.1998.5463. PMID 9790748. 
  2. 2.0 2.1 "Entrez Gene: VPS52 vacuolar protein sorting 52 homolog (S. cerevisiae)". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6293. 

Further reading