Biology:WNT2B

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A representation of the 3D structure of the protein myoglobin showing turquoise α-helices.
Generic protein structure example

Protein Wnt-2b (formerly Wnt13[1]) is a protein that in humans is encoded by the WNT2B gene.[2][3][4]

This gene encodes a member of the wingless-type MMTV integration site (WNT) family of highly conserved, secreted signaling factors. WNT family members function in a variety of developmental processes including regulation of cell growth and differentiation and are characterized by a WNT-core domain. This gene may play a role in human development as well as human carcinogenesis. This gene produces two alternative transcript variants.[4]

References

  1. "Wnt2b controls retinal cell differentiation at the ciliary marginal zone". Development 130 (3): 587–98. 2003. doi:10.1242/dev.00244. PMID 12490564. 
  2. "Cloning, expression and chromosomal localization of Wnt-13, a novel member of the Wnt gene family". Oncogene 13 (4): 873–6. Oct 1996. PMID 8761309. 
  3. "Alternative splicing of the WNT-2B/WNT-13 gene". Biochem Biophys Res Commun 275 (1): 209–16. Sep 2000. doi:10.1006/bbrc.2000.3252. PMID 10944466. 
  4. 4.0 4.1 "Entrez Gene: WNT2B wingless-type MMTV integration site family, member 2B". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7482. 

Further reading