Biology:XPC-binding
From HandWiki
| XPC-binding | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 solution structure of xpc binding domain of hhr23b | |||||||||
| Identifiers | |||||||||
| Symbol | XPC-binding | ||||||||
| Pfam | PF09280 | ||||||||
| InterPro | IPR015360 | ||||||||
| SCOP2 | 1pve / SCOPe / SUPFAM | ||||||||
| |||||||||
In molecular biology, the XPC binding domain is thought to play a role in DNA damage discrimination and in the enhancement of cell survival.[1] They bind specifically and directly to the xeroderma pigmentosum group C protein (XPC) to initiate nucleotide excision repair (NER).[1] Members of this entry adopt a structure consisting of four alpha helices, arranged in an array.
References
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