Biology:ZNF160
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Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
Zinc finger protein 160 is a protein that, in humans, is encoded by the ZNF160 gene.[1][2][3]
The protein encoded by this gene is a Krüppel-related zinc finger protein which is characterized by the presence of an N-terminal repressor domain, the Kruppel-associated box (KRAB). The KRAB domain is a potent repressor of transcription; thus this protein may function in transcription regulation. Two alternative transcripts encoding the same isoform have been described.[3]
References
- ↑ "A novel C2H2 zinc-finger protein gene (ZNF160) maps to human chromosome 19q13.3-q13.4". Genomics 25 (1): 322–3. Jul 1995. doi:10.1016/0888-7543(95)80149-G. PMID 7774943.
- ↑ "Isolation of cDNA clones for 42 different Kruppel-related zinc finger proteins expressed in the human monoblast cell line U-937". DNA Cell Biol 14 (2): 125–36. Mar 1995. doi:10.1089/dna.1995.14.125. PMID 7865130.
- ↑ 3.0 3.1 "Entrez Gene: ZNF160 zinc finger protein 160". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=90338.
Further reading
- "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55–65. 2006. doi:10.1101/gr.4039406. PMID 16344560.
- "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. 2004. doi:10.1038/ng1285. PMID 14702039.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "Molecular cloning and preliminary functional analysis of two novel human KRAB zinc finger proteins, HKr18 and HKr19.". DNA Cell Biol. 20 (5): 275–86. 2001. doi:10.1089/104454901750232472. PMID 11410164.
- "Characterization of long cDNA clones from human adult spleen.". DNA Res. 7 (6): 357–66. 2001. doi:10.1093/dnares/7.6.357. PMID 11214971.
- "Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.". DNA Res. 7 (4): 273–81. 2001. doi:10.1093/dnares/7.4.271. PMID 10997877.
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