Biology:ZRSR2
From HandWiki
Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2 is a protein that in humans is encoded by the ZRSR2 gene.[1][2][3][4]
This gene encodes an essential splicing factor. The encoded protein associates with the U2 auxiliary factor heterodimer, which is required for the recognition of a functional 3' splice site in pre-mRNA splicing, and may play a role in network interactions during spliceosome assembly.[4]
References
- ↑ "Isolation and mapping of human homologues of an imprinted mouse gene U2af1-rs1". Genomics 30 (2): 257–63. Mar 1996. doi:10.1006/geno.1995.9879. PMID 8586425.
- ↑ "A protein related to splicing factor U2AF35 that interacts with U2AF65 and SR proteins in splicing of pre-mRNA". Nature 388 (6640): 397–400. Aug 1997. doi:10.1038/41137. PMID 9237760. Bibcode: 1997Natur.388..397T.
- ↑ "The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome". RNA 10 (6): 929–41. May 2004. doi:10.1261/rna.7320604. PMID 15146077.
- ↑ 4.0 4.1 "Entrez Gene: ZRSR2 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8233.
Further reading
- "Genomic structure and comparative analysis of nine Fugu genes: conservation of synteny with human chromosome Xp22.2-p22.1.". Genome Res. 9 (5): 437–48. 1999. doi:10.1101/gr.9.5.437. PMID 10330123.
- "Antigens recognized by autologous antibody in patients with renal-cell carcinoma.". Int. J. Cancer 83 (4): 456–64. 1999. doi:10.1002/(SICI)1097-0215(19991112)83:4<456::AID-IJC4>3.0.CO;2-5. PMID 10508479.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. 2004. doi:10.1038/ng1285. PMID 14702039.
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. 2004. doi:10.1101/gr.2596504. PMID 15489334.
- "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. 2006. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
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