Chemistry:1,6-Dichloro-1,6-dideoxyfructose
From HandWiki
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| Names | |
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| IUPAC name
(3S,4S,5S)-1,6-dichloro-3,4,5-trihydroxyhexan-2-one
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| Identifiers | |
3D model (JSmol)
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PubChem CID
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| Properties | |
| C6H10Cl2O4 | |
| Molar mass | 217.04 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
1,6-Dichloro-1,6-dideoxyfructose (dichlorodideoxyfructose)[1][2][3] is chlorinated derivative of the sugar fructose. It is one of the two components believed to comprise the disaccharide sucralose,[4] a commercial sugar substitute.
Metabolism
In mammals, 1,6-dichloro-1,6-dideoxyfructose is metabolized in the liver and erythrocytes by a reaction with glutathione that replaces one of the chlorine atoms, forming 6-chlorofructos-1-yl glutathione (or chlorofructosyl glutathione).[5]
References
- ↑ Hough, L. (1993), Khan, Riaz, ed., "High-intensity, low-calorie sweeteners" (in en), Low-Calorie Foods and Food Ingredients (Boston, MA: Springer US): pp. 138–164, doi:10.1007/978-1-4615-3114-2_7, ISBN 978-1-4615-3114-2, https://doi.org/10.1007/978-1-4615-3114-2_7, retrieved 2022-11-24
- ↑ PubChem. "1,6-Dichloro-1,6-dideoxyfructose" (in en). https://pubchem.ncbi.nlm.nih.gov/compound/3081555.
- ↑ "1,6-dichloro-1,6-dideoxyfructose | C6H10Cl2O4 | ChemSpider". http://www.chemspider.com/Chemical-Structure.2339136.html.
- ↑ Labare, M. P.; Alexander, M. (1994-10-01). "Microbial cometabolism of sucralose, a chlorinated disaccharide, in environmental samples" (in en). Applied Microbiology and Biotechnology 42 (1): 173–178. doi:10.1007/BF00170242. ISSN 1432-0614. PMID 7765816. https://doi.org/10.1007/BF00170242.
- ↑ Hughes, H M; Powell, G M; Snodin, D J; Daniel, J W; Crawford, A; Sanders, J K; Curtis, C G (15 April 1989). "Glutathione-dependent dechlorination of 1,6-dichloro-1,6-dideoxyfructose". Biochemical Journal 259 (2): 537–543. doi:10.1042/bj2590537. PMID 2719664.
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