Chemistry:2,4-Xylidine

From HandWiki

2,4-Xylidine is an organic compound with the formula C6H3(CH3)2NH2. It is one of several isomeric xylidines. It is a colorless viscous liquid. Commercially significant derivatives include the veterinary drug cymiazole and the colorant Pigment Yellow 81.[1]

Genotoxic and teratogenic, 2,4‑xylidine is an industrial pollutant.[2] In addition, it is a degradant of the pesticide amitraz at very acidic pH values (<3).[relevant? ][3]

It is prepared by nitration of m-xylene followed by hydrogenation.

References

  1. Meyer, M. (2012). "Xylidines". Ullmann's Encyclopedia of Industrial Chemistry. Weinheim: Wiley-VCH. doi:10.1002/14356007.a28_455. ISBN 978-3527306732. 
  2. Brimecombe, R. D.; Fogel, R.; Limson, J. L. (2006). "Electrochemical monitoring of the biodegradation of 2,4-dimethylaniline". Journal of Agricultural and Food Chemistry 54 (23): 8799–8803. doi:10.1021/jf061951k. PMID 17090125. 
  3. Corta, E. W.; Bakkali, A.; Berrueta, L. A.; Gallo, B.; Vicente, F. (1999). "Kinetics and mechanism of amitraz hydrolysis in aqueous media by HPLC and GC-MS". Talanta 48 (1): 189–199. doi:10.1016/s0039-9140(98)00237-9. PMID 18967458.