Chemistry:2-Methylserine
From HandWiki
2-Methylserine is a non-proteinogenic amino acid that is structurally similar to serine. Like serine, it is polar, and therefore soluble in water. It differs structurally from serine by the presence of a methyl group on the backbone carbon.
2-Methylserine is one of the amino acids produced by an unpublished volcanic-spark discharge experiment conducted by Stanley Miller in the early 1950s. However, the presence of this and many other organic compounds was not discovered until Jeffrey Bada et al. re-analyzed the contents of the vials from Miller's experiment in 2008.[1]
References
- ↑ Johnson, Adam P.; Cleaves, H. James; Dworkin, Jason P.; Glavin, Daniel P.; Lazcano, Antonio; Bada, Jeffrey L. (2008-10-17). "The Miller Volcanic Spark Discharge Experiment". Science 322 (5900): 404. doi:10.1126/science.1161527. ISSN 0036-8075. PMID 18927386. Bibcode: 2008Sci...322..404J.
Further reading
- Anson, Michael S.; Clark, Hugh F.; Evans, Paul; Fox, Martin E.; Graham, Jonathan P.; Griffiths, Natalie N.; Meek, Graham; Ramsden, James A. et al. (2011-03-18). "Complementary Syntheses of N,O-Protected-(S)-2-methylserine on a Multikilogram Scale". Organic Process Research & Development 15 (2): 389–397. doi:10.1021/op100299d. ISSN 1083-6160.
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