Chemistry:3-Mercaptopyruvic acid
From HandWiki
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| Names | |
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| Preferred IUPAC name
2-Oxo-3-sulfanylpropanoic acid | |
| Other names
3-Mercapto-2-oxopropanoic acid
3-MPV 3-MP | |
| Identifiers | |
3D model (JSmol)
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| KEGG | |
| MeSH | 3-mercaptopyruvic+acid |
PubChem CID
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| Properties | |
| C3H4O3S | |
| Molar mass | 120.12 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
 verify (what is   ?)
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| Infobox references | |
3-Mercaptopyruvic acid is an intermediate in cysteine metabolism. It has been studied as a potential treatment for cyanide poisoning, but its half-life is too short for it to be clinically effective.[1] Instead, prodrugs, such as sulfanegen, are being evaluated to compensate for the short half-life of 3-mercaptopyruvic acid.[2]
See also
References
- ↑ Nagahara, N; Li, Q; Sawada, N (2003). "Do antidotes for acute cyanide poisoning act on mercaptopyruvate sulfurtransferase to facilitate detoxification?". Current Drug Targets. Immune, Endocrine and Metabolic Disorders 3 (3): 198–204. doi:10.2174/1568008033340162. PMID 12871026.
- ↑ Brenner, M; Kim, JG; Lee, J; Mahon, SB; Lemor, D; Ahdout, R; Boss, GR; Blackledge, W et al. (2010). "Sulfanegen sodium treatment in a rabbit model of sub-lethal cyanide toxicity". Toxicology and Applied Pharmacology 248 (3): 269–76. doi:10.1016/j.taap.2010.08.002. PMID 20705081.
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