Chemistry:4-Cyano-3-(trifluoromethyl)aniline
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| Names | |
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| Preferred IUPAC name
4-Amino-2-(trifluoromethyl)benzonitrile | |
| Other names
4-Cyano-3-(trifluoromethyl)aniline
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| Identifiers | |
3D model (JSmol)
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PubChem CID
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| Properties | |
| C8H5F3N2 | |
| Molar mass | 186.137 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
Tracking categories (test):
4-Cyano-3-(trifluoromethyl)aniline, also known as 4-amino-2-(trifluoromethyl)benzonitrile, is a cyanated and trifluoromethylated derivative of aniline. It is the starting material in one of the chemical syntheses of the nonsteroidal antiandrogen bicalutamide.[1]
References
- ↑ "Nonsteroidal antiandrogens. Synthesis and structure-activity relationships of 3-substituted derivatives of 2-hydroxypropionanilides". Journal of Medicinal Chemistry 31 (5): 954–9. 1988. doi:10.1021/jm00400a011. PMID 3361581.
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