Chemistry:4-Thiouridine

From HandWiki

4-Thiouridine is an atypical nucleoside formed with the 4-thiouracil base found in transfer RNA (tRNA).[1] Its biosynthesis has been determined.[2]

The IUPAC reserved the single-letter nucleobase code "S" for thiouridine in 1970, but the convention does not appear very common.[3] "S" was repurposed to mean "C or G" in 1984.[4]

References

  1. Alberts, Bruce (18 November 2014). Molecular biology of the cell (Sixth ed.). New York, NY. pp. 337. ISBN 978-0-8153-4432-2. OCLC 887605755. 
  2. Park, Chung-Min; Weerasinghe, Laksiri; Day, Jacob J.; Fukuto, Jon M.; Xian, Ming (2015). "Persulfides: Current knowledge and challenges in chemistry and chemical biology". Molecular BioSystems 11 (7): 1775–1785. doi:10.1039/c5mb00216h. PMID 25969163. 
  3. IUPAC-IUB Commission on Biochemical Nomenclature (1970). "Abbreviations and symbols for nucleic acids, polynucleotides, and their constituents". Biochemistry 9 (20): 4022–4027. doi:10.1021/bi00822a023. 
  4. Nomenclature Committee of the International Union of Biochemistry (NC-IUB) (1984). "Nomenclature for Incompletely Specified Bases in Nucleic Acid Sequences". Nucleic Acids Research 13 (9): 3021–3030. doi:10.1093/nar/13.9.3021. PMID 2582368.