Chemistry:7,8-Dihydroneopterin triphosphate

7,8-Dihydroneopterin triphosphate

Names
Preferred IUPAC name (2R,3S)-3-(2-Amino-4-oxo-3,4,7,8-tetrahydropteridin-6-yl)-2,3-dihydroxypropyl tetrahydrogen triphosphate
Other names DHNTP
Identifiers
CAS Number	17088-65-2 N
3D model (JSmol)	Interactive image Interactive image
ChEBI	CHEBI:18372 Y
ChemSpider	108735 Y
KEGG	C04895
PubChem CID	121885
InChI InChI=1S/C9H16N5O13P3/c10-9-13-7-5(8(17)14-9)12-3(1-11-7)6(16)4(15)2-25-29(21,22)27-30(23,24)26-28(18,19)20/h4,6,15-16H,1-2H2,(H,21,22)(H,23,24)(H2,18,19,20)(H4,10,11,13,14,17)/t4-,6+/m1/s1 Y Key: DGGUVLXVLHAAGT-XINAWCOVSA-N Y InChI=1/C9H16N5O13P3/c10-9-13-7-5(8(17)14-9)12-3(1-11-7)6(16)4(15)2-25-29(21,22)27-30(23,24)26-28(18,19)20/h4,6,15-16H,1-2H2,(H,21,22)(H,23,24)(H2,18,19,20)(H4,10,11,13,14,17)/t4-,6+/m1/s1 Key: DGGUVLXVLHAAGT-XINAWCOVBB
SMILES O=C1C2=C(NCC([C@@H]([C@@H](COP(OP(OP(O)(O)=O)(O)=O)(O)=O)O)O)=N2)NC(N)=N1 O=P(O)(O)OP(=O)(O)OP(=O)(O)OC[C@@H](O)[C@@H](O)C/1=N/C=2C(=O)\N=C(/NC=2NC\1)N
Properties
Chemical formula	C9H16N5O13P3
Molar mass	495.170 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)
Infobox references

Tracking categories (test):

• SizeSet

7,8-Dihydroneopterin triphosphate (DHNTP) is an intermediate in tetrahydrobiopterin biosynthesis. It is transformed by 6-pyruvoyltetrahydropterin synthase into 6-pyruvoyl-tetrahydropterin. It is also used in the Queuosine/Archeosine Pathway.

Synonyms

• Dihydroneopterin Triphosphate
• 7,8-dihydroneopterin 3'-triphosphate
• 6-(L-erythro-1,2-Dihydroxypropyl 3-triphosphate)-7,8-dihydropterin
• 6-[(1S,2R)-1,2-dihydroxy-3-triphosphooxypropyl]-7,8-dihydropterin
• 6-(L-erythro-1,2-dihydroxy-3-triphosphooxypropyl)-7,8-dihydropterin
• 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)dihydropteridine triphosphate
• 2-Amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)dihydropteridinetriphosphate
• (2R,3S)-3-(2-amino-4-oxo-3,4,7,8-tetrahydropteridin-6-yl)-2,3-dihydroxypropyl tetrahydrogen triphosphate