Chemistry:8-Hydroxyguanosine

8-Hydroxyguanosine

Names
IUPAC name 2-Amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-2-tetrahydrofuranyl]-3,7-dihydropurine-6,8-dione
Other names 8-Oxoguanosine
Identifiers
CAS Number	3868-31-3 N
3D model (JSmol)	Interactive image Interactive image
ChEMBL	ChEMBL1688964 N
ChemSpider	228049 Y
PubChem CID	65131
InChI InChI=1S/C10H13N5O6/c11-9-13-6-3(7(19)14-9)12-10(20)15(6)8-5(18)4(17)2(1-16)21-8/h2,4-5,8,16-18H,1H2,(H,12,20)(H3,11,13,14,19) Y Key: FPGSEBKFEJEOSA-UHFFFAOYSA-N Y InChI=1/C10H13N5O6/c11-9-13-6-3(7(19)14-9)12-10(20)15(6)8-5(18)4(17)2(1-16)21-8/h2,4-5,8,16-18H,1H2,(H,12,20)(H3,11,13,14,19) Key: FPGSEBKFEJEOSA-UHFFFAOYAG
SMILES C(C1C(C(C(O1)N2C3=C(C(=O)N=C(N3)N)NC2=O)O)O)O O=C3/N=C(/N)NC\1=C3\NC(=O)N/1C2OC(C(O)C2O)CO
Properties
Chemical formula	C10H13N5O6
Molar mass	299.24 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)
Infobox references

Tracking categories (test):

• SizeSet

8-Hydroxyguanosine is an RNA nucleoside which is an oxidative derivative of guanosine. Measurement of the levels of 8-hydroxyguanosine is used as a biomarker of oxidative stress causing RNA damage.

See also

• 8-Oxo-2'-deoxyguanosine