Chemistry:A-286501
From HandWiki
A-286501 is an experimental drug that acts as a selective inhibitor of the enzyme adenosine kinase. In animal studies it has analgesic and antiinflammatory effects.[1][2][3]
References
- ↑ "Cyclic cis-1,3-Diamines Derived from Bicyclic Hydrazines: Synthesis and Applications". Synlett 32 (9): 858–874. 2021. doi:10.1055/s-0040-1707324. https://hal.science/hal-03003668/file/SYNLETT%20revised.pdf.
- ↑ "Analgesic and anti-inflammatory effects of A-286501, a novel orally active adenosine kinase inhibitor". Pain 96 (1–2): 107–118. March 2002. doi:10.1016/s0304-3959(01)00435-3. PMID 11932067.
- ↑ "Comparison of the ability of adenosine kinase inhibitors and adenosine receptor agonists to attenuate thermal hyperalgesia and reduce motor performance in rats". Pharmacology, Biochemistry, and Behavior 73 (3): 573–581. October 2002. doi:10.1016/s0091-3057(02)00840-7. PMID 12151032.
 |  |
