Chemistry:ADTL-SA1215

From HandWiki

ADTL-SA1215 is a drug which acts as a sirtuin-3 (SIRT3) activator. It has been researched as a potential therapeutic agent for the treatment of triple negative breast cancer, as well as being used for basic research into the structure and function of the SIRT3 enzyme complex.[1][2]

References

  1. "Structure-Guided Design of a Small-Molecule Activator of Sirtuin-3 that Modulates Autophagy in Triple Negative Breast Cancer". Journal of Medicinal Chemistry 64 (19): 14192–14216. October 2021. doi:10.1021/acs.jmedchem.0c02268. PMID 34605238. 
  2. "Current Trends in Sirtuin Activator and Inhibitor Development". Molecules 29 (5): 1185. March 2024. doi:10.3390/molecules29051185. PMID 38474697.