Chemistry:AXC-715

From HandWiki

AXC-715 is a drug which acts as an agonist at Toll-like receptor 7 (TLR7) and Toll-like receptor 8 (TLR8), with modest selectivity for TLR7. It acts as an immunostimulant, and has broad spectrum antiviral effects in animal models, and is also of interest as a potential anti-cancer drug.[1][2]

References

  1. "Antibody-drug conjugates for targeted cancer therapy: Recent advances in potential payloads". European Journal of Medicinal Chemistry 276. 2024. doi:10.1016/j.ejmech.2024.116709. PMID 39068862. 
  2. "A Novel Small-Molecule TLR7 Agonist AXC-715 Stabilizes TLR7 Dimerization and Exhibits Broad-Spectrum Antiviral Activity". Microorganisms 14 (4): 862. 2026. doi:10.3390/microorganisms14040862. PMID 42075261.