Chemistry:Actinobolin

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Actinobolin
Actinobolin.svg
Names
IUPAC name
(2S)-2-Amino-N-[(3R,4R,4aR,5R,6R)-5,6,8-trihydroxy-3-methyl-1-oxo-3,4,4a,5,6,7-hexahydroisochromen-4-yl]propanamide[1]
Other names
(Propanamide, 2-amino-N-(3,4,4a,5,6,7-hexahydro-5,6, 8-trihydroxy-3-met hyl-1-oxo-1H-2-benzopyran-4-yl)-
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
UNII
Properties
C13H20N2O2
Molar mass 236.315 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
Tracking categories (test):

Actinobolin is a antibiotic with the molecular formula C13H20N2O6.[1] Actinobolin is produced by the bacterium Streptomyces griseoviridus var atrofaciens.[2]

References

  1. 1.0 1.1 "Actinobolin" (in en). Pubchem.ncbi.NLM.nih.gov. https://pubchem.ncbi.nlm.nih.gov/compound/Actinobolin#section=3D-Conformer. 
  2. (in en) Studies in Natural Products Chemistry: Stereoselective Synthesis (Part J). Elsevier. 10 August 1995. p. 3. ISBN 978-0-08-054178-5. 

Further reading

  • Tharra, Prabhakara R.; Mikhaylov, Andrey A.; Švejkar, Jiří; Gysin, Marina; Hobbie, Sven N.; Švenda, Jakub (28 February 2022). "Short Synthesis of (+)-Actinobolin: Simple Entry to Complex Small-Molecule Inhibitors of Protein Synthesis". Angewandte Chemie International Edition 61 (17): e202116520. doi:10.1002/anie.202116520. PMID 35167723. 
  • (in en) Antimicrobial Agents and Chemotherapy. 1958. p. 503. 
  • Munk, Morton E.; Sodano, Charles S.; McLean, Robert L.; Haskell, Theodore H. (August 1967). "Actinobolin. I. Structure of actinobolamine". Journal of the American Chemical Society 89 (16): 4158–4165. doi:10.1021/ja00992a034. PMID 6045607.