Chemistry:Aganodine
From HandWiki
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| IUPAC name
2-(4,7-Dichloro-1,3-dihydroisoindol-2-yl)guanidine
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3D model (JSmol)
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PubChem CID
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| Properties | |
| C9H10Cl2N4 | |
| Molar mass | 245.109 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
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Tracking categories (test):
Aganodine is a guanidine that activates presynaptic imidazoline receptors.[1] Through its agonism at imidazoline receptors, aganodine inhibits the presynaptic release of norepinephrine.[2]
References
- ↑ Molderings, GJ; Likungu, J; Jakschik, J; Göthert, M (1997). "Presynaptic imidazoline receptors and non-adrenoceptor 3H-idazoxan binding sites in human cardiovascular tissues". British Journal of Pharmacology 122 (1): 43–50. doi:10.1038/sj.bjp.0701343. PMID 9298527.
- ↑ Göthert, M.; Brüss, M.; Bönisch, H.; Molderings, G.J. (1999). "Presynaptic Imidazoline Receptors". Annals of the New York Academy of Sciences 881: 171–184. doi:10.1111/j.1749-6632.1999.tb09356.x. PMID 10415912.
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