Chemistry:Betaenone
From HandWiki
Betaenones are phytotoxins found in the fungus Pleospora betae.[1] The compounds were found to inhibit a variety of protein kinases.[2]
Members of this class of chemical compounds include:
Two further betaenones were found in a species of the fungus Microsphaeropsis, which was isolated from the marine sponge Aplysina aerophoba.[3]
References
- ↑ Ichihara A.; Oikawa, Hideaki; Hayashi, Kazuko; Sakamura, Sadao; Furusaki, Akio; Matsumoto, Takeshi (1983). "Structures of Betaenones A and B, Novel Phytotoxins from Phoma betae Fr.". J. Am. Chem. Soc. 105 (9): 2907–2908. doi:10.1021/ja00347a070. Bibcode: 1983JAChS.105.2907I.
- ↑ Patrick, D.; Heimbrook, D (1996). "Protein kinase inhibitors for the treatment of cancer.". Drug Discovery Today 1 (8): 325–330. doi:10.1016/1359-6446(96)10030-1.
- ↑ Brauers, G. (2000). "Anthraquinones and Betaenone Derivatives from the Sponge-Associated Fungus Microsphaeropsis Species: Novel Inhibitors of Protein Kinases.". Journal of Natural Products 63 (6): 739–745. doi:10.1021/np9905259. PMID 10869191. Bibcode: 2000JNAtP..63..739B.
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