Chemistry:CDD-2807

From HandWiki

CDD-2807 is a chemical compound which acts as a potent and selective inhibitor of serine/threonine-protein kinase 33 (STK33), with a IC50 of 9.2 nM. In animal studies it causes production of abnormal sperm with reduced motility, and it has been investigated as a potential male contraceptive drug.[1][2]

See also

References

  1. ↑ "An emerging target for male contraception". Science 384 (6698): 849–850. May 2024. doi:10.1126/science.adp6432. PMID 38781397. Bibcode: 2024Sci...384..849H. 
  2. ↑ "Reversible male contraception by targeted inhibition of serine/threonine kinase 33". Science 384 (6698): 885–890. May 2024. doi:10.1126/science.adl2688. PMID 38781365. Bibcode: 2024Sci...384..885K. 



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