Chemistry:CU-CPT4a
From HandWiki
Short description: Chemical compound
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| Formula | C18H13ClFNO3S |
| Molar mass | 377.81 g·mol−1 |
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CU-CPT4a is a drug which acts as a selective antagonist of Toll-like receptor 3 (TLR3), with an IC50 of 3.44 μM. It is used for research into the function of TRL3 and its role in inflammation, autoimmune disorders and cancer.[1][2]
See also
- CU-CPT9a
References
- ↑ "A Reproducibility-Based Computational Framework Identifies an Inducible, Enhanced Antiviral State in Dendritic Cells from HIV-1 Elite Controllers". Genome Biology 19 (1): 10. January 2018. doi:10.1186/s13059-017-1385-x. PMID 29378643.
- ↑ "Receptor-interacting protein kinase 1 is a key mediator in TLR3 ligand and Smac mimetic-induced cell death and suppresses TLR3 ligand-promoted invasion in cholangiocarcinoma". Cell Communication and Signaling 18 (1): 161. October 2020. doi:10.1186/s12964-020-00661-3. PMID 33036630.
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