Chemistry:Carmantadine
From HandWiki
Carmantadine (INN, USAN; developmental code name SCH-15427) is an antiparkinsonian agent of the adamantane group that was never marketed.[1][2][3][4] It is structurally related to amantadine and shares some of its pharmacological actions.[2] Another related drug is dopamantine.[2][3][4] Carmantadine was first described by 1972 and is said to have reached early clinical trials.[1][2][3][4]
References
- ↑ 1.0 1.1 The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer US. 2014. p. 13. ISBN 978-1-4757-2085-3. https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA13. Retrieved 13 September 2024.
- ↑ 2.0 2.1 2.2 2.3 "Chapter 3. Antiparkinsonism Drugs". Annual Reports in Medicinal Chemistry. 9. Elsevier. 1974. pp. 19–26. doi:10.1016/s0065-7743(08)61424-4. ISBN 978-0-12-040509-1. https://books.google.com/books?id=rZBH1_7Tx6UC&pg=PA21. "Carmantadine (VII, Sch 151427) is structurally related to amantadine33. It shares some of its pharmacological actions, was effective in a head—turning test34 and is in early clinical trials."
- ↑ 3.0 3.1 3.2 "Pharmacology of Dopamantine and Carmantadine, 2 Potential Antiparkinson Agents". Pharmacologist 16 (2): 205–. January 1974. https://scholar.google.com/scholar?cluster=11299450660035123147.
- ↑ 4.0 4.1 4.2 "Antagonism of electrically-induced heart-turning (HT) following intracaudate administration of dopamine (DA), amantadine (AM), apomorphine (APO), dopamantine and carmantadine". Pharmacologist 16 (2): 206. January 1974. https://eurekamag.com/research/026/136/026136837.php.
 |  |
