Chemistry:Cary–Blair transport medium
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Cary–Blair transport medium is a solution used to preserve fecal clinical specimens and rectal swabs after collection. The medium was devised by Sylvia G. Cary and Eugene B. Blair in 1964,[1] who noted it allowed for longer-term recovery of Salmonella, Shigella, Vibrio, and Pasteurella than other transport media.
Cary–Blair transport medium is a modification of a solution devised by R.D. Stuart, S.R. Toshach and T.M. Patsula in 1954[2] which allowed for high recoverability of Gonococci from fecal samples. Cary and Blair noted Stuart, Toshach and Patsula's medium and other solutions that allowed for long-term recovery of pathogens from feces were characterized by low nutrient content, low oxidation-reduction potential, and high pH.
As of 2024, the use of Cary–Blair transport medium is recommended by the United States Center for Disease Control for laboratory testing of epidemic dysentery and cholera if culture will not begin within two hours[3]
References
- ↑ Cary, S. G.; Blair, E. B. (1964). "NEW TRANSPORT MEDIUM FOR SHIPMENT OF CLINICAL SPECIMENS I. : Fecal Specimens". Journal of Bacteriology 88 (1): 96–98. doi:10.1128/jb.88.1.96-98.1964. PMID 14197911.
- ↑ STUART RD; TOSHACH SR; PATSULA TM (1954). "The problem of transport of specimens for culture of Gonococci". Canadian Journal of Public Health 45 (2): 73–83. PMID 13126855.
- ↑ Laboratory Methods for the Diagnosis of Epidemic Dysentery and Cholera (Manual). United States CDC. June 26, 2024. p. 7. https://www.cdc.gov/cholera/media/pdfs/2024/07/Chapter-2-Laboratory-methods-for-the-diagnosis-of-epidemic-dysentery-and-cholera_ENG-2.pdf.
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