Chemistry:Chondroitin
A chondroitin, as the sulfate, is a component of bamacan, a proteoglycan (sugar-protein conjugate) that comprises some membranes.[1] Condroitin is a chondrin derivative.[2]
Types include:
Chondroitin as a supplement is now commonly used (often in combination with glucosamine) in treating the joint disease of osteoarthritis.[3] In contrast to the symptomatic treatments, chondroitin can modify the progression of a disease process in the patient which it can be used as an alternative medicine.[3] Chondroitin's effect toward the articular cartilage integrity as it is part of the proteoglycan molecules.[4] The cartilage proteoglycan synthesis can speed up as chondroitin is going through the pathway of the alimentary canal.[4] Research has been conducted to show the effectiveness of chondroitin and results indicate that it helps to manage pain in knee and hip, slow down the progression and also recovery.[5] However, the effectiveness of the drugs is still doubtful.[4]
References
- ↑ Iozzo, Renato V. (1998). "MATRIX PROTEOGLYCANS: From Molecular Design to Cellular Function". Annual Review of Biochemistry 67: 609–652. doi:10.1146/annurev.biochem.67.1.609. PMID 9759499.
- ↑ Chondroitin at the US National Library of Medicine Medical Subject Headings (MeSH)
- ↑ 3.0 3.1 Vasiliadis, Haris S; Tsikopoulos, Konstantinos (2017). "Glucosamine and chondroitin for the treatment of osteoarthritis" (in en). World Journal of Orthopedics 8 (1): 1–11. doi:10.5312/wjo.v8.i1.1. ISSN 2218-5836. PMID 28144573.
- ↑ 4.0 4.1 4.2 Tavakol, Kamran. "Glucosamine and Chondroitin for Treatment of Osteoarthritis: A Systematic Quality Assessment and Meta-analysis". Physical Therapy 80 (10): 1049.
- ↑ Zhu, Xiaoyue; Sang, Lingli; Wu, Dandong; Rong, Jiesheng; Jiang, Liying (December 2018). "Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials" (in en). Journal of Orthopaedic Surgery and Research 13 (1): 170. doi:10.1186/s13018-018-0871-5. ISSN 1749-799X. PMID 29980200.
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