Chemistry:Curvularin
From HandWiki
Curvularin is an antimicrobial chemical compound produced by Penicillium and Curvularia.[1]
Characteristics
| Characteristic | Value |
|---|---|
| Number of hydrogen bond acceptors | 5 |
| Number of hydrogen bond donors | 2 |
| Number of rotating bonds | 0 |
| Partition coefficient[2] (ALogP) | 3.0 |
| Solubility[3] (logS, log(mol/L)) | -2.8 |
| Polar surface area[4] (PSA, Å2) | 83.8 |
References
- ↑ Savchuk, IaI; Zaĭchenko, AM; Tsyganenko, ES (July 2012). "Biological activity of Penicillium sp. 10-51 exometabolites". Mikrobiolohichnyi Zhurnal 74 (4): 52–6. PMID 23088100.
- ↑ Ghose, Arup K.; Viswanadhan, Vellarkad N.; Wendoloski, John J. (1998). "Prediction of Hydrophobic (Lipophilic) Properties of Small Organic Molecules Using Fragmental Methods: An Analysis of ALOGP and CLOGP Methods". The Journal of Physical Chemistry A 102 (21): 3762–3772. doi:10.1021/jp980230o. Bibcode: 1998JPCA..102.3762G.
- ↑ Ghose, Arup K.; Viswanadhan, Vellarkad N.; Wendoloski, John J. (1998-05-01). "Prediction of Hydrophobic (Lipophilic) Properties of Small Organic Molecules Using Fragmental Methods: An Analysis of ALOGP and CLOGP Methods" (in en). The Journal of Physical Chemistry A 102 (21): 3762–3772. doi:10.1021/jp980230o. ISSN 1089-5639. Bibcode: 1998JPCA..102.3762G. https://pubs.acs.org/doi/10.1021/jp980230o.
- ↑ Ertl, Peter; Rohde, Bernhard; Selzer, Paul (2000-10-01). "Fast Calculation of Molecular Polar Surface Area as a Sum of Fragment-Based Contributions and Its Application to the Prediction of Drug Transport Properties" (in en). Journal of Medicinal Chemistry 43 (20): 3714–3717. doi:10.1021/jm000942e. ISSN 0022-2623. PMID 11020286. https://pubs.acs.org/doi/10.1021/jm000942e.
External links
 |  |
