Chemistry:Dehydrocurvularin
From HandWiki
Dehydrocurvularin also known as Curvularin is an antimicrobial made by Penicillium.[1] It was first isolated in 1967.[2] It has been shown to possess antifungal properties against Candida albicans and Candida auris,[3] as well as nematicidal efficacy against Root-knot nematode and Root-lesion nematode.[4]
References
- ↑ Savchuk, IaI; Zaĭchenko, A. M.; Tsyganenko, E. S. (2012). "Biological activity of Penicillium sp. 10-51 exometabolites". Mikrobiolohichnyi Zhurnal 74 (4): 52–6. PMID 23088100.
- ↑ Munro, H. D.; Musgrave, O. C.; Templeton, Richard (1967). "Curvularin. Part V. The compound C 16 H 18 O 5 , αβ-dehydrocurvularin" (in en). J. Chem. Soc. C 0: 947–948. doi:10.1039/J39670000947. ISSN 0022-4952. https://pubs.rsc.org/j3/article/255655.
- ↑ Kamauchi, Hitoshi; Furukawa, Miho; Kiba, Yuka; Kitamura, Masashi; Usui, Kanako; Katakura, Masanori; Takao, Koichi; Sugita, Yoshiaki (September 2022). "Antifungal activity of dehydrocurvularin for Candida spp. through the inhibition of adhesion to human adenocarcinoma cells" (in en). The Journal of Antibiotics 75 (9): 530–533. doi:10.1038/s41429-022-00543-5. ISSN 1881-1469. PMID 35859164. https://www.nature.com/articles/s41429-022-00543-5.
- ↑ Xiang, Chao; Liu, Ying; Liu, Shi-Ming; Huang, Ya-Fei; Kong, Ling-An; Peng, Huan; Liu, Mao-Yan; Liu, Jing et al. (2020-03-04). "αβ-Dehydrocurvularin isolated from the fungus Aspergillus welwitschiae effectively inhibited the behaviour and development of the root-knot nematode Meloidogyne graminicola in rice roots". BMC Microbiology 20 (1): 48. doi:10.1186/s12866-020-01738-2. ISSN 1471-2180. PMID 32126973.
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