Chemistry:Dithiobutylamine
From HandWiki
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| Names | |
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| Preferred IUPAC name
(S)-2-aminobutane-1,4-dithiol | |
| Other names
DTBA
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| Identifiers | |
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3D model (JSmol)
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| ChemSpider | |
PubChem CID
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| Properties | |
| C4H11NS2 | |
| Molar mass | 137.26 g/mol |
| Appearance | White solid[1] |
| Odor | Nearly odorless[1] |
| Soluble | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
Dithiobutylamine (DTBA) is a reducing agent intended as an alternative for DTT in biochemical uses. It was designed to be easily synthesized in non-racemic form, to have a lower pKa (allowing more effective reduction at neutral pH), and to have a low disulfide E°′ reduction potential.[1] It was rationally designed & reported in 2012.[1] It is commercially available.
See also
- Dithiothreitol (DTT)
- 2-Mercaptoethanol (BME)
- TCEP
References
- ↑ 1.0 1.1 1.2 1.3 1.4 Lukesh, John C.; Palte, Michael J.; Raines, Ronald T. (2012-02-21). "A Potent, Versatile Disulfide-Reducing Agent from Aspartic Acid". Journal of the American Chemical Society (American Chemical Society (ACS)) 134 (9): 4057–4059. doi:10.1021/ja211931f. ISSN 0002-7863. PMID 22353145.
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