Chemistry:Elacomine
From HandWiki
Elacomine is a natural oxindole alkaloid found in the plant species Elaeagnus commutata.[1]
Synthethic routes for obtaining this compound have been described, based on 2-halotryptamines.[1] Different approaches, such as regiospecific synthesis, were also mentioned.[2]
It is a member of the spiroindolone class (specifically, a spirooxindolopyrrolizidine derivative). Horsfiline has a similar chemical structure.
References
- ↑ 1.0 1.1 "Preparation and Synthetic Applications of 2-Halotryptamines: Synthesis of Elacomine and Isoelacomine". Organic Letters 6 (5): 711–713. 2004. doi:10.1021/ol030138x.
- ↑ "Regiospecific synthesis and biological evaluation of spirooxindolopyrrolizidines via [3+2] cycloaddition of azomethine ylide". European Journal of Medicinal Chemistry 45 (12): 6120–6126. 2010. doi:10.1016/j.ejmech.2010.09.051. PMID 20947223.
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