Chemistry:Elaiomycin
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Elaiomycin is an antimicrobial chemical compound, classified as an conjugated azoxyalkene, which was first isolated from Streptomyces in 1954.[1][2] A laboratory synthesis of elaiomycin was reported in 1977.[3]
A variety related compounds, collectively called elaiomycins, have also been reported.[4][5]
References
- ↑ Haskell, Theodore H.; Ryder, Albert; Bartz, Quentin R. (1954). "Elaiomycin, a new tuberculostatic antibiotic; isolation and chemical characterization". Antibiotics & Chemotherapy (Northfield, Ill.). Antibiotics and Chemotherapy 4 (2): 141–144. PMID 24542889.
- ↑ Erlich, J.; Anderson, LE; Coffey, GL; Feldman, WH; Fisher, MW; Hillegas, AB; Karlson, AG; Knudsen, MP et al. (1954). "Elaiomycin, a new tuberculostatic antibiotic; biologic studies". Antibiotics & Chemotherapy (Northfield, Ill.). Antibiotics and Chemotherapy 4 (3): 338–342. PMID 24542957.
- ↑ "The synthesis of elaiomycin, a naturally occurring azoxyalkene". Journal of the American Chemical Society 99 (5): 1643–5. March 1977. doi:10.1021/ja00447a060. PMID 839012. Bibcode: 1977JAChS..99.1643M.
- ↑ Helaly, Soleiman E.; Pesic, Alexander; Fiedler, Hans-Peter; Süssmuth, Roderich D. (2011). "Elaiomycins B and C: Alkylhydrazide Antibiotics from Streptomyces sp. BK 190". Organic Letters 13 (5): 1052–1055. doi:10.1021/ol1031014. PMID 21309518.
- ↑ "Elaiomycins D-F, antimicrobial and cytotoxic azoxides from Streptomyces sp. strain HKI0708". Journal of Natural Products 75 (10): 1729–34. October 2012. doi:10.1021/np300329m. PMID 23013356. Bibcode: 2012JNAtP..75.1729D.
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