Chemistry:Enmetazobactam
From HandWiki
Enmetazobactam (AAI-101) is an antibiotic adjuvant drug which acts as a beta-lactamase inhibitor, preventing the breakdown of other antibiotic drugs.[1] Enmetazobactam was invented by a team of scientists at Orchid Pharma in India and then out-licensed to Allecra Therapeutics for further development.[2] In the United States and European Union, enmetazobactam is approved for use in the combination cefepime/enmetazobactam (Exblifep).[3][4]
References
- ↑ "Cefepime-Enmetazobactam: A Drug Review of a Novel Beta-Lactam/Beta-Lactamase Inhibitor". The Annals of Pharmacotherapy 59 (6): 570–576. September 2024. doi:10.1177/10600280241279904. PMID 39329253.
- ↑ US patent No.7687488B2 Novel 2-substituted methyl penam derivatives, https://worldwide.espacenet.com/patent/search/family/038949982/publication/US7687488B2?q=pn%3DUS7687488
- ↑ (PDF) New Drug Therapy Approvals 2024 (Report). January 2025. https://www.fda.gov/media/184967/download. Retrieved 21 January 2025.
- ↑ "Exblifep EPAR". 25 January 2024. https://www.ema.europa.eu/en/medicines/human/EPAR/exblifep. Text was copied from this source which is copyright European Medicines Agency. Reproduction is authorized provided the source is acknowledged.
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