Chemistry:Flusilazole

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Flusilazole
Flusilazol1.svg
Flusilazole-3D-balls.png
Names
Preferred IUPAC name
1-{[Bis(4-fluorophenyl)(methyl)silyl]methyl}-1H-1,2,4-triazole
Other names
DPX-H6573;
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
UNII
Properties
C16H15F2N3Si
Molar mass 315.392 g/mol
41.9 mg/L (20°C)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references
Tracking categories (test):

Flusilazole (DPX-H6573) is an organosilicon fungicide invented by DuPont, which is used to control fungal infections on a variety of fruit and vegetable crops.[1][2][3] It is moderately toxic to animals and has been shown to produce birth defects in high doses.[4][5]

References

  1. Moberg, W. K.; Basarab, G. S.; Cuomo, J.; Liang, P. H. (1987). "Biologically Active Organosilicon Compounds". Synthesis and Chemistry of Agrochemicals. ACS Symposium Series. 355. pp. 288–301. doi:10.1021/bk-1987-0355.ch026. ISBN 9780841214347. 
  2. "Baseline toxicity of several pesticides to Hyaliodes vitripennis (Say) (Hemiptera: Miridae)". Pest Management Science 57 (11): 1007–10. November 2001. doi:10.1002/ps.374. PMID 11721516. 
  3. "Effects of fungicides on in vitro spore germination and mycelial growth of the phytopathogens Leptosphaeria maculans and L. biglobosa (phoma stem canker of oilseed rape)". Pest Management Science 66 (4): 396–405. April 2010. doi:10.1002/ps.1890. PMID 20013877. 
  4. "Developmental toxic effects of antifungal flusilazole administered by gavage to mice". Birth Defects Research Part B: Developmental and Reproductive Toxicology 80 (1): 12–7. February 2007. doi:10.1002/bdrb.20098. PMID 17187383. 
  5. "Relative embryotoxicity of two classes of chemicals in a modified zebrafish embryotoxicity test and comparison with their in vivo potencies". Toxicology in Vitro 25 (3): 745–753. January 2011. doi:10.1016/j.tiv.2011.01.005. PMID 21238576. 

External links

  • Flusilazole in the Pesticide Properties DataBase (PPDB)