Chemistry:GP3269
From HandWiki
GP3269 is an experimental drug that acts as a selective inhibitor of the enzyme adenosine kinase. In animal studies it has analgesic and anticonvulsant effects.[1][2][3]
References
- ↑ "Design, Synthesis and Anticonvulsant Activity of the Potent Adenosine Kinase Inhibitor GP3269.". Nucleosides and Nucleotides 16 (7–9): 1013–1021. 1997. doi:10.1080/07328319708006124.
- ↑ "Adenosine kinase inhibitors. 6. Synthesis, water solubility, and antinociceptive activity of 5-phenyl-7-(5-deoxy-beta-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidines substituted at C4 with glycinamides and related compounds". Journal of Medicinal Chemistry 48 (24): 7808–7820. December 2005. doi:10.1021/jm050394a. PMID 16302820.
- ↑ "Novel trends in the treatment of cardiovascular disorders: site- and event- selective adenosinergic drugs". Current Medicinal Chemistry 18 (8): 1164–1187. 2011. doi:10.2174/092986711795029753. PMID 21291368.
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