Chemistry:Gludantan
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Gludantan, or gludantane, is an experimental antiparkinsonian agent of the adamantane group that was never marketed.[1][2] It has also been described as a "psychotropic" and antidepressant.[3] An analogue of gludantan, N-3,5-dimethylgludantan, is an inactive metabolite of memantine.[4][5] Gludantan was developed in the Soviet Union and was first described by 1974.[6][2]
See also
- Hemantane
- List of Russian drugs
References
- ↑ "Adamantane derivatives: Pharmacological and toxicological properties (review)". Pharmaceutical Chemistry Journal 34 (1): 1–7. 2000. doi:10.1007/BF02524549. ISSN 0091-150X.
- ↑ 2.0 2.1 "Ob antiparkinsonicheskoĭ aktivnosti gludantana (predvaritel'noe soobshchenie)" (in Russian). Zhurnal Nevropatologii I Psikhiatrii imeni S.S. Korsakova 75 (6): 910–916. 1975. PMID 1217399.
- ↑ "Adamantylpyridines and their biological activities". Pharmaceutical Chemistry Journal 24 (1): 31–35. 1990. doi:10.1007/BF00769382. ISSN 0091-150X.
- ↑ "Memantine". Drugs & Aging 20 (6): 465–476; discussion 477–478. 2003. doi:10.2165/00002512-200320060-00005. PMID 12710865.
- ↑ "The efficacy and safety of memantine for the treatment of Alzheimer's disease". Expert Opinion on Drug Safety 17 (10): 1053–1061. October 2018. doi:10.1080/14740338.2018.1524870. PMID 30222469.
- ↑ "The present and future of specific prophylaxis of influenza and other acute viral respiratory diseases". The American Review of Respiratory Disease 110 (5): 537–541. November 1974. doi:10.1164/arrd.1974.110.5.537. PMID 4611289.
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