Chemistry:Hyclate

From HandWiki

A hyclate (Latin: hyclas) is a pharmaceutical term for hydrochloride hemiethanolate hemihydrate[1][2]HCl·1/2EtOH·1/2H2O), e.g. doxycycline hyclate.[3][4]

References

  1. "hyclate". https://medical-dictionary.thefreedictionary.com/hyclate. Retrieved 5 June 2018. 
  2. Legendre, Alexandre O.; Silva, Laila R. R.; Silva, Douglas M.; Rosa, Iara M. L.; Azarias, Lilian C.; de Abreu, Polyana J.; de Araújo, Magali B.; Neves, Person P. et al. (2012). "Solid state chemistry of the antibiotic doxycycline: structure of the neutral monohydrate and insights into its poor water solubility". CrystEngComm 14 (7): 2532–2540. doi:10.1039/C1CE06181J. 
  3. "Doxycycline hyclate – Final text to replace published monograph in The International Pharmacopoeia". https://www.who.int/medicines/publications/pharmacopoeia/QAS06_185FINAL_DoxyHyclateRevMonoNov07.pdf. Retrieved 5 June 2018. 
  4. Note: As of June 2018, doxycycline hyclate is apparently the only known, or used hyclate.