Chemistry:Icafolin-methyl
From HandWiki
Icafolin-methyl is a post-emergent chemical herbicide developed by Bayer.[1] It is a methyl ester derivative of icafolin and has the formula C
18H
18F
2N
2O
5.[2] The herbicide was patented in 2022,[3] registered in 2025, and is anticipated to be introduced in 2028 for use in Brazil.[4] It is a tubulin inhibitor that may be applied to cereals, oilseeds and soybeans, and is described as being effective against monocotyledonous and dicotyledonous weeds, with examples being sourgrass and barnyardgrass.[5] The herbicide is synthesized as a mixture of (2R,4R) and (2S,4S) stereoisomers through a multi-step process.[2] Icafolin-methyl is hydrolyzed to icafolin in plants.[6]
References
- ↑ Young, Cyndi. "Bayer Unveils Icafolin and Conventro: New Herbicide Technologies Target Resistant Weeds and Support Sustainable Farming" (in en-US). https://www.brownfieldagnews.com/news/bayer-unveils-icafolin-and-conventro-new-herbicide-technologies-target-resistant-weeds-and-support-sustainable-farming/.
- ↑ 2.0 2.1 Template:Cite PubChem
- ↑ "Icafolin-methyl". University of Hertfordshire. 9 November 2025. https://sitem.herts.ac.uk/aeru/ppdb/en/Reports/3550.htm.
- ↑ Marston, Jennifer (2025-09-30). "Icafolin-methyl 'a completion of glyphosate,' not a replacement: in conversation with Bayer" (in en-US). https://agfundernews.com/icafolin-methyl-a-completion-of-glyphosate-not-a-replacement-in-conversation-with-bayer.
- ↑ "Bayer should launch two herbicides in the coming years: icafolin and Convintro Duo" (in en). January 2, 2024. https://revistacultivar.com/news/bayer-should-launch-two-herbicides-in-the-coming-years-icafolin-and-convintro-duo.
- ↑ Haaf, Klaus-Bernhard; Peters, Olaf; Laber, Bernd; Lange, Gudrun; Gatzweiler, Elmar; Geibel, Sven; Passon, Daniel; Endler, Anne et al. (2025). "The novel herbicide icafolin-methyl is a plant-specific inhibitor of tubulin polymerization". Pest Management Science 81 (5): 2652–2661. doi:10.1002/ps.8415. ISSN 1526-4998. PMID 39297346.
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